As an example, have a look at the image below. The most powerful extract is the dual extract (hot water/ethanol)
on the right. It has twice the volume of the hot water-only extract. So volume-wise the hot water extract might be 14:1 and the dual extract only 7:1, but to draw the conclusion the 14:1 extract is the most potent one would be wrong. A basic hot water extract (freeze dried) and a full spectrum dual extract (spray dried). The dual extract's particle size is much smaller but the total volume is larger. Smaller particles means better absorption and solubility, which improves bio-availability and therefore therapeutic effect.